Higher Risk for Kidney Stones in Ankylosing Spondylitis
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Saturday, September 24, 2016 12:00 AM

Patients with ankylosing spondylitis were at an increased risk of developing kidney stones, Taiwanese researchers found.

In a population-based cohort study, newly diagnosed nephrolithiasis was found to be 19% more common in patients with ankylosing spondylitis compared with individuals without the disease.

The majority of kidney stones contain calcium, and patients with severe ankylosing spondylitis have been shown to have altered calcium and vitamin D metabolism. They also have an increased risk of inflammatory bowel disease, which can elevate their absorption of calcium and oxalate. Further contributing to the risk of nephrolithiasis is their use of anti-inflammatory drugs and immobilization

Our results showed that patients with ankylosing spondylitis are more likely to be associated with nephrolithiasis than non-ankylosing spondylitis patients,” researchers concluded.  The overall frequency of nephrolithiasis in the ankylosing spondylitis cohort was 4.8%.

Source:  http://www.medpagetoday.com/Rheumatology/Arthritis/59925