Less Sugar May Mean Better Insulin Sensitivity in Obese Children
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Monday, December 21, 2015 07:19 AM

Restricting sugar led to improved insulin sensitivity in a small trial, pointing to the role of fructose on metabolic syndrome, researchers said.  When 43 children with obesity cut their dietary sugar from 28% to 10% of their diet and replaced it with starches, their metabolic parameters improved significantly after 9 days.

Children in the trial had lost a substantial amount of hepatic fat (22%) and visceral fat (7.3%), but not subcutaneous fat; and fasting insulin, initial area under the curve (IAUC), c-peptide, and Composite Insulin Sensitivity Index (CISI) improved.

They found that the improved insulin sensitivity was due to changes in liver fat, and not changes in the visceral fat. "The visceral fat played no role.  This says that we can fix obese children's metabolic health in 9 days on the same number of calories, without changing subcutaneous fat." 

"These data support the assertion that fructose restriction should be an integral modality to improve metabolic status in children with obesity, irrespective of weight loss," concluded the researchers.

Source:  http://www.medpagetoday.com/MeetingCoverage/ObesityWeek/54585