Beta-Blockers During Surgery Can Increase Mortality Risk
Written by Editor   
Wednesday, June 17, 2015 03:27 PM
Quick Brief: It is now clear that a patient without cardiac risk factors should NOT be started on a beta-blocker before a major surgery.


"Our study is the first to show this risk increase in this population.  It is now clear that a patient with no cardiac risk factors should not be started on a beta-blocker for a major surgery."

Prescribing perioperative beta-blockers for noncardiac surgery was associated with a higher risk for death in patients with no cardiac risk factors in a retrospective analysis, but the practice appeared to reduce mortality in patients with three or four cardiac risk factors.

Perioperative beta-blocker use has been shown to benefit cardiac surgery patients, but the practice remains highly controversial in noncardiac surgery patients with a low-to-moderate risk of having heart-related events.

In the newly published analysis, which included close to 326,500 noncardiac surgery patients, beta-blockade was found to significantly lower death risk in patients with three to four cardiac risk factors

Beta-blockade appeared to have no impact on patients with one to two cardiac risk factors, but its use was associated with a significantly higher risk of death in patients with no cardiac risk factors.