Antioxidants in Blood Tied to Better Cognition
Thursday, January 15, 2015 04:13 PM

Blood concentrations of some antioxidative micronutrients were positively associated with executive function and visuopractical skills, researchers reported. Among healthy patients, plasma concentrations of non-provitamin A were positively and significantly associated with executive function, before and after adjustment for body mass index (BMI), smoking status, diabetes, hypertension, and cardiac disease.  Additionally, concentrations of provitamin A were positively and significantly associated with visuopractical skills before and after adjustment.

Past research has shown positive relationships between diet and memory, including one study that tied omega-3 and vitamin consumption to healthy cognition in older adults, and another that showed slowed cognitive decline in older patients who consumed a diet low in fat and high in nuts, vegetables, and legumes.  However, these studies have not based results on actual plasma concentration of the micronutrients potentially associated with healthier minds.

The investigators analyzed plasma concentrations of 10 antioxidative micronutrients.  Plasma was analyzed for concentrations of alpha-carotene, beta-carotene, beta-crytoxanthin, canthaxanthin, lutein and zeaxanthin, lycopene, alpha-tocopherol, gamma-tocopherol, and vitamin C through reverse phase chromatography.